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AbbVie Scientist l, Drug Product Development in South San Francisco, California

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok (https://www.tiktok.com/@abbvie) .

Job Description

The Drug Product Development group within AbbVie is a global organization responsible for developing and characterizing drug product formulations and manufacturing processes for biologic therapeutics (antibodies, antibody-drug conjugates (ADCs), neurotoxins, and novel biologic formats) from preclinical development through clinical proof of concept.

We have an exciting opportunity for a Scientist I to join our team at our Bay Area site in South San Francisco, CA. This role is an onsite role in a lab-based function. To be successful candidates must enjoy and thrive in an onsite, highly collaborative lab environment with daily face-to-face cross functional interactions between scientists.

KEY RESPONSIBILITIES INCLUDE:

Develop and optimize biologic (antibodies, antibody fragments, bispecifics, antibody-drug conjugates (ADCs), neurotoxins, cytokines, peptides, etc) drug product formulations to enable clinical studies in a phase appropriate manner.

  • Independently design, investigate, identify, and execute formulation development, drug product process development, and in-use studies to ensure formulation stability and dose accurate administration.

  • Perform routine and complex tasks independently and competently and modifies plans in alignment with manager and team. Seeks technical input when needed.

  • Investigate, identify, optimize new protocols, formulations, characterization methods, and techniques to promote innovation while ensuring reliability, reproducibility and scale-ability.

  • Interpret results and draw conclusions from experiments, noting significant deviations and scientific questions, and suggests and pursue relevant experiments.

  • Demonstrates technical proficiency in drug product development projects and works efficiently and collaboratively towards project timelines and goals.

  • Read and adapt scientific literature to accomplish assignments and demonstrate broad and versatile technical expertise within drug product development to answer scientific questions.

  • Understands and adheres to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug, and GxP compliance where applicable.

  • Generate high-quality data based on sound scientific principles and document results in electronic lab notebook.

  • Effectively organize and present scientific data in presentations and document studies by authoring reports that support regulatory filings.

  • Effectively communicate study plans, update, data and conclusions to team members in a clear and timely manner.

  • May contribute to writing and conceptual framework of publications, presentations and patents.

Qualifications

  • Must possess a Bachelor’s Degree in Chemistry, Biochemistry, Biology, Chemical Engineering, Pharmaceutical Sciences, or equivalent with typically 4-5 years of experience, or Master’s Degree or equivalent education with typically two years of industry experience.

  • Experience in biologic formulation development for liquid and lyophilized products.

  • Experience in biologic drug product process development and hand-on experience with filler, liquid handlers, lyophilizer, etc.

  • Strong experience in computational/programming skills for automation of workflows and data processing (Hamilton liquid handlers or other automation instruments)

  • Hands-on experience in analytical techniques used for protein characterization and stability testing required (e.g., SEC, CE-SDS, icIEF, HIAC, MFI, DLS, etc.)

  • Detail-oriented and highly organized with a demonstrated ability to and solve technical challenges.

  • Excellent oral and written communication, attention to detail, and ability to keep detailed written records in lab notebook on a daily basis.

  • Ability to learn, understand and execute new scientific techniques

  • Ability to multi-task and work within timelines with strong planning and analytical skills.

Ability to work collaboratively within and outside of the group.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​

  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

  • This job is eligible to participate in our short-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Salary: $71,000 - $134,500

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