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Job Title: Scientist Consultant, Antibody Discovery (PhD)

Location: San Francisco, CA

Shift: M-F 8-5

Type: Contract, 1 year

Pay : Up to $84.75/hour depending upon experience

Qualifications:

• PhD in Biochemistry, Biomedical/Chemical Engineering, Immunology, or related field with minimum of 2 years of post-graduate experience (preferably in industry), MS with 8+ years of research experience, BS with 10+ years of research experience in antibody or protein engineering

• Significant experience in antibody discovery and protein engineering by using single B cell cloning, hybridoma, or phage/yeast display techniques

• Strong background in molecular biology, antibody and protein expression, and biophysical characterization of recombinant antibodies and proteins

• Demonstrated experience in working collaboratively across various scientific disciplines and other parts of the organization to meet end goals

• Highly motivated individual with exceptionally good organizational skills, and attention to details

• Demonstrate ability to succeed in a fast-paced environment, working on multiple projects with constantly changing priorities and deadlines

• Excellent written and verbal communication skills

• Strong interpersonal skills

  Additional Preferences:

• Experience in single domain antibodies, multi-specific antibody engineering, Fc engineering, antibody drug conjugates, naïve phage or yeast display library design

• Experience in NGS analysis for antibody discovery and engineering

• Significant contributions to successful biologics drug discovery programs in biotech/biopharma industry

  Responsibilities:

• Design strategies and execute antibody discovery campaigns for therapeutic and reagent antibodies using phage display

• Generate antibody fragment libraries for antibody discovery and engineering, perform HT binding screens (ELISA and multi-plex flow cytometry) and sequence analysis to generate hits

• Rank-order clones by affinity, in vitro potency, and early developability assessment

• Execute sequence optimization of lead antibodies to improve developability and binding affinity

• Design and clone constructs for mAbs, bispecific, and multi-specific antibodies for recombinant antibody production

• Support NGS-based antibody discovery workflow

• Present data and updates to management and project teams

• Follow good documentation practice including maintaining good record keeping in Electronic Notebooks

  Benefits

  System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan.

System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.