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Responsibilities: The SEPS lab () at the Center for Integrative Brain Research, Seattle Children's Research Institute and the University of Washington invites applications for an R01-funded postdoctoral position focusing on CAR T cell signaling. Work in the SEPS lab focuses on signal transduction through protein-protein interaction networks, and employs a unique technology called Quantitative Multiplex co-Immunoprecipitation or QMI. Using QMI and molecular genetic techniques, the successful applicant will lead a project examining how specific protein interactions engaged by the CAR contribute to CAR T cell efficacy, and how patient-to-patient variability in protein levels may contribute to detrimental side effects. The successful candidate will work closely with a technician and graduate/undergraduate students to plan and supervise several parallel lines of investigation, using primary human T cells or banked patient material from completed trials. The candidate will be expected to independently move projects forward, write papers, and apply for F32 or equivalent grants. The ideal candidate will have the ability to perform precise wetlab work and complex bioinformatics analyses using MatLab and R programming. Prior experience in immunology, molecular biology, and/or CAR T cell therapy is a plus. Creative, big-picture thinking and dedication academic research are essential. The selected candidate will join the vibrant research community at CIBR, located on the newly renovated 8thfloor of the Jack MacDonald building in downtown Seattle. A modern, open lab space, a collegial atmosphere, on-site gym and rooftop garden, and top-of-the-line equipment, office space and meeting rooms make this an ideal training environment. Emailed inquiries toare always welcomed. Requirements: Required Education/Experience: Doctorate degree (PhD/DVM/MD) in specialty area from an accredited university training program. Experience using basic research techniques of specialty area. Required Credentials: N/A. Preferred: Previous experience conducting research in the pediatric arena. Experience in protocol and manuscript development and in grant writing. Min to Max Hourly Salary: $31.48 - $47.39 /hr Min to Max Annual Salary: $65,478.40 - $98,571.20 /yr Salary Information: This compensation range was calculated based on full-time employment (2080 hours worked per calendar year). Offers are determined by multiple factors including equity, skills, experience, and expertise, and may vary within the range provided. Disclaimer for Out of State Applicants: This compensation range is specific to Seattle, positions located outside of Seattle may be compensated differently depending on various factors. Benefits Information: Seattle Children's offers a generous benefit package, including medical, dental, and vision plans, 403(b), life insurance, paid time off, tuition reimbursement, and more. for more information. About Us: Hope. Care. Cure. These three simple words capture what we do at Seattle Children's - to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care, and cures to help every child live the healthiest and most fulfilling life possible. Our investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine. Researchers work in close collaboration with o