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The Department of Pathology and Cell Biology is seeking highly motivated individuals to join The Laboratory of Transfusion Biology. Our lab studies the red blood cell (RBC) and platelet (patho)physiology, factors that affect component quality for transfusion, and initiation of immune responses to RBC and platelet auto- and allo-antigens. The proposed projects include: (1) genetic and environmental factors that modulate RBC and platelet function during health and disease, (2) identification of risk factors for RBC and platelet alloimmunization, (3) elucidation of mechanisms underpinning enhanced alloimmune responses to reticulocytes, (4) understanding how the storage lesion affects individual RBC populations and platelets, (5) elucidating the mechanisms that lead to tolerance failure to RBC and platelet autoantigens, and (6) defining how diet and exercise affect RBC storage quality in vitro and post-transfusion efficacy in vivo. Most projects have require work with both murine models and samples from humans.

At CUIMC, we stand together because diverse experiences, perspective, and values enrich every dimension of our work. Join our team and see how your unique skills and experiences can create a real impact by changing lives.

Job Function:

• 50% - Performing experiments
• 20% - Reading/Writing scientific manuscripts
• 20% - Recording/analyzing data
• 5% - General lab maintenance
• 5% - Other duties as required

Skills frequently utilized to complete daily tasks include: mouse handling, basic lab skills (e.g. pipetting, loading a gel), DNA extraction and PCR, flow cytometry, and sterile technique.

Lab Mission/Purpose:

Our mission as leaders in transfusion medicine is to drive scientific research and innovation in blood banking and transfusion therapy. We are committed to advancing the science and practice of transfusion medicine through cutting-edge research and collaboration with leading experts in the field. https://www.pathology.columbia.edu/research/clinical-and-translational-research/laboratory-transfusion-biology

Minimum Education Requirements:

Requires a Ph.D. and/or M.D. with sufficient experience in basic science or translational research, a record of independent and collaborative research, and excellent written and verbal communication skills.

Minimum Skills Required:

Candidate should have knowledge of basic laboratory techniques (e.g., pipetting) and equipment (e.g., centrifuge), as well as the ability to follow standard operating procedures.

Preferred Qualifications:

A strong preference will be given to candidates with a broad knowledge of immunology, transgenic mouse models, and flow cytometry. Advanced knowledge of RBCs, erythropoiesis, stress erythropoiesis, oxidative biology, and/or alloimmunity is preferred.

Hiring Salary Range: $70,000-$70,000