New York Genome Center Postdoctoral Research Associate (Computational Biology), Vickovi Lab in New York, New York
The Vickovi Lab at the New York Genome Center, Columbia University's Fu Foundation School of Engineering and Applied Science and Columbia University's Herbert and Florence Irving Institute for Cancer Dynamics is looking for a motivated individual to work as an Associate Research Scientist I within a creative and dynamic research team of scientists and engineers. The Vickovi Lab is focused on developing novel "digital pathology" tools to track disease progression with the aim of identifying translatable drug and therapeutic targets in human tissue cohorts. The team leverages technologies including spatial transcriptomics, single-cell sequencing, and machine learning. A particular area of disease focus for the lab is developing tools for spatial genomics that will enable perturbing highly complex interactions in the human gut-to-brain axis.
We are looking for a motivated computational biologist to join our team, lead the development and application of new approaches in the field of single cell and spatial genomics and specifically those with experience and interest in multi-modal data integration including DNA chromatin conformation and imaging data. As a Postdoctoral Research Associate, you will be a critical member of a collaborative team with opportunities to contribute to innovative research projects. You will investigate and test new methods and technologies for project advancement, in order to understand the mechanisms of neuroimmunology, cancer immunology and aging, in an efficient and comprehensive manner, which will accelerate the advancement of clinical therapeutic hypotheses. The Vickovi Lab works closely with the Technology Innovation Lab; a leading biohub for molecular biology innovation located at NYGC.
Responsibilities may include:
Develop new computational, machine learning, and statistical analysis methods for integrating and analyzing large-scale, spatially resolved RNA-seq and genotypic data using current state of the art technologies;
Develop a resource for the community that gives access to collected data;
Work closely with experimental colleagues and cores to understand the nature of generated data;
Actively participate in the preparation of manuscripts for publication and present at scientific conferences;
Assist in peer- and student-mentorship; and
Share expertise and provide training and guidance to group members as needed.
Relevant PhD degree required, with a strong computational biology or computer science focus.
Extensive knowledge and experience of modern molecular biology and/or chemistry tools required, including next-generation sequencing methods; single-cell and spatial genomics.
A proven track record in computational methods development required;
Ability to work in an independent manner with minimal supervision but having a strong collaborative personality required;
Excellent interpersonal skills and ability to work efficiently in a dynamic, multidisciplinary environment required;
Strong research, problem solving, and communication skills (both written and oral) required, coupled with a strong attention to detail and scientific curiosity; and,
Excellent analytical and organizational skills required.
Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations, and delivers on commitments.
Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so.
Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity.
The Postdoctoral Research Associate will be expected to meet regularly with Dr. Vickovic at NYGC and Columbia University's Biomedical Engineering Department. This individual will also interact regularly with faculty at both institutions. The fellow will participate in regular group meetings at both NYGC and Columbia, and will participate in meetings of NYC-wide working groups.
About the New York Genome Center
The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer's, Parkinson's, Huntington's), and cancer.
Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community.
Please note: We care greatly about our employees' wellbeing, so NYGC has moved to a fully COVID-19 vaccinated work environment. You must be vaccinated against COVID-19 to work at NYGC, even if you are working partially remotely. If you are selected to interview for this role, we will explain our vaccination policy (including medical and religious exemptions) and ensure you are comfortable moving forward with further interviews.
Diversity, equity, and inclusion are central to the core mission at the NYGC. We strive to create a workplace environment that is welcoming and fair to all regardless of race, ethnicity, gender, sexual orientation, physical ability, or religion. We believe that when people of various backgrounds, life experiences, and perspectives work together in an inclusive and equitable environment we gain new and valuable perspectives that otherwise would have been missed. Valuing and supporting all NYGC employees as individuals while helping them realize their full potential is critical to promoting greater collaboration, innovation, and discovery - fostering a sense of belonging for our greatest strength, our people. We recognize that there is still work to be done that will require sustained commitment from the entire organization.
The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.
FLSA Status - Exempt
This position is eligible for visa sponsorship and relocation assistance.
New York, New York, United States
The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.