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St. Jude Children's Research Hospital Bioinformatics Research Scientist in Memphis, Tennessee

The Molecular Pathology group of the Department of Pathology at St. Jude Children’s Research Hospital (SJCRH) is seeking a highly motivated Bioinformatics Research Scientist. This is an opportunity to implement bioinformatics solutions in next generation sequencing (NGS) and maintain large informatics systems under the direction of Molecular Pathology Leaders.

The Molecular Pathology group uses whole-genome sequencing (WGS), whole exome sequencing (WES), whole transcriptome sequencing (RNA-seq) and target-capture NGS testing for oncology and genetic diagnosis for all patients managed at SJCRH. This group provides comprehensive molecular profiling for all cancer types which would assist clinicians in determining disease diagnosis, risk stratification, prognosis, and treatment options, including targeted therapies and eligibility for clinical trials. We are one of very few clinical laboratories in the US who use the most cutting-edge sequencing platforms, WGS and whole transcriptome sequencing, for oncology molecular diagnosis.

The comprehensive genetic tests developed by Molecular Pathology and Computational Biology at SJCRH involve sequencing the genome of the tumor and the matched normal specimen. These germline findings in cancer predisposition genes could have a significant impact in the clinical management of patients and their families.

The Molecular Pathology team provides a highly interactive environment with collaborative opportunities with Computational Biology Department and Center of Applied Bioinformatics at SJCRH, access to high performance pipelines and computing clusters, a cloud computing environment, innovative visualization tools, and mentorship from senior scientists with expertise in data analysis, data management and delivery of high-quality results. This team supports strong teamwork as well as personal career development.

  • Programming of bioinformatics pipelines for NGS testing in clinical diagnostics

  • Supports clinical operations and lab informatics systems

  • Performs data analysis, data visualization, statistical analysis, experimental design, database development, mathematical modeling, and novel method development

  • Provides bioinformatics analysis on patients’ samples and communicates analytical process and results with Molecular Pathologists

  • Assists in preparing clinical reports

  • Contributes ideas to automate or improve existing analysis methods, and innovative algorithm development

  • Assists with establishing and documenting protocols or best practices for NGS-based clinical tests

  • Ensures that efficient and prompt help is provided to Molecular Pathology directors and faculty

  • Bachelor's degree is required

  • Masters or PhD prefered

  • Seven (7) years of relevant post-degree work experience is required

  • Five (5) years of relevant post-degree work experience is required with a Master's degree

  • Two (2) years of relevant post-degree work experience is required with a PhD

Salary is highly competitive (comparable to industry) and employee benefits are outstanding. Relocation assistance is available. Working at St. Jude provides the opportunity to make a tangible difference to pediatric cancer patient care and survival and St. Jude has been consistently ranked in Fortune magazine’s “100 Best Places to Work” list and is exceptionally positively reviewed on GlassDoor.

St. Jude is an Equal Opportunity EmployerNo Search Firms:St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.COVID-19 vaccine:St. Jude Children’s Research Hospital has mandated the COVID-19 vaccine for all employees, excluding those with an approved medical or religious accommodation, as a condition of employment.

WITS Req ID: 48495

Street: 262 Danny Thomas Place