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The Eschweiler lab in the Department of Experimental Therapeutics is seeking a highly motivated postdoctoral researcher for a position in cancer immunology. This research will involve investigating the cellular/molecular dynamics of innate and adaptive immune cells to develop novel immunotherapy strategies in solid tumors. In this regard, both basic and translational studies employ xenografts, genetically engineered mouse models, and patient specimens. A wide set of cellular, basic immunology, advanced flow cytometry, molecular, and transcriptome analysis techniques will be utilized to interrogate pertinent questions in several in vitro and in vivo studies. The lab employs genomic tools, novel mouse tumor models, and computational approaches to understand the immunological basis of cancer.

LEARNING OBJECTIVES

The applicant should be self-motivated, able to design and conduct experiments, prepare, and present their work at meetings, and write scientific manuscripts; should have skill in setting up and use of laboratory equipment, and the ability to assist with the development of new and improved methodology. The applicant is expected to train students/technologists when necessary and participate in overall lab management.

Preferred Job-Specific Competencies:

• Ability to work with In vivo mouse models

• Skilled in the following analytical techniques:

• Tumor immunology & cancer immunotherapy

• Mouse handling & injection skills (Intraperitoneal, subcutaneous, retroorbital)

• Cell culture of various cancer cell lines & primary cells

• Multi-color flow cytometry (FACS) & cell sorting

• Single-cell RNA-seq & ATAC-seq

• Data analysis & interpretation

• Other duties as assigned.

ELIGIBILITY REQUIREMENTS

PhD degree in cancer biology, molecular biology, genetics, immunology, or related fields.

Candidates with immunology background and experience and with at least one first-author publication in immunology/basic immunology in medium-high impact journals + experience in mouse models, and advanced flow-cytometry acquisition/analysis expertise.

Preferred Experience:

Evidence of strong scientific productivity demonstrated by high-quality research published in peer-reviewed journals. Skills for internal and collaborative projects. A strong sense of curiosity and willingness to explore different avenues.

ADDITIONAL APPLICATION INFORMATION

Consideration of application will begin immediately and continue until the position is filled.

POSITION INFORMATION

MD Anderson follows the NIH stipend levels as outlined by the Kirchstein - NRSA (https://grants.nih.gov/grants/guide/notice-files/NOT-OD-23-076.html) . This full-time trainee position will provide a salary between $56,484 to $68,604, dependent upon the years of postgraduate experience.

MD Anderson offers compensated trainees:

• Paid medical benefits (zero premium) starting on first day for trainees who work 30 or more hours per week

• Group Dental, Vision, Life, AD&D and Disability coverage

• Paid Education Vacation and Sick Leave

• Paid institutional holidays, wellness leave, childcare leave and other paid leave programs

• Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans

• Employer paid life, AD&D and an illness-related reduced salary pay program

• Health Savings Account and Dependent Care Reimbursement flexible spending accounts

• Fertility benefits

• State of Texas longevity pay

• Extensive wellness, fitness, employee health programs and employee resource groups

FACULTY MENTOR

Simon Eschweiler, PHD