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Postdoctoral positions are available to study molecular mechanisms associated with therapeutic response and resistance in non-small cell lung cancer (NSCLC) in the laboratory of John V. Heymach, MD, PhD at the University of Texas MD Anderson Cancer Center in Houston, TX. The lab is largely interested in the development of rationale treatment strategies for KRAS, EGFR, and HER2 mutant NSCLC with a focus on overcoming resistance to targeted therapies, identifying targetable metabolic adaptations, and enhancing response to immunotherapy. Applicants with experience in any of these areas are encouraged to apply and provide three professional references.

LEARNING OBJECTIVES

Trainees will perform translational research involving molecular biology approaches (such as CRISPR/Cas technology, Western blotting, ELISA, immunohistochemistry), in vitro assays (such as drug screening, flow cytometry, development of resistant cell lines, metabolic profiling) and in vivo experiments using xenograft, syngeneic and genetically engineered mouse models of lung cancer. Trainees will present their findings at regular lab meetings, departmental seminars, and national conferences. Trainees will submit their findings for publication in peer-reviewed scientific journals.

ELIGIBILITY REQUIREMENTS

Applications are invited from qualified individuals interested in working in a translational research lab; with a PhD and/or MD. The preferred candidate should have less than 2 years of prior postdoctoral experience with a background in mouse models studying cancer biology, cell biology, molecular biology, or immunology and be highly motivated to pursue an independent career in biomedical research.

Job Knowledge and Skills:

1. Enthusiastic, highly self-motivated candidate with the ability to function independently

2. A strong background in cell and molecular biology, immunology, or metabolic signaling

3. Dedication to basic research, a true "drive", is important

4. Prior experience with studies involving mice is preferred

5. Command of written and spoken English language

6. Prior publication record

POSITION INFORMATION

MD Anderson follows the NIH stipend levels as outlined by the "Kirchstein - NRSA". This full-time trainee position will provide a salary between $56,484 to $68,604, dependent upon the years of postgraduate experience.

MD Anderson offers compensated trainees:

• Paid medical benefits (zero premium) starting on first day for trainees who work 30 or more hours per week

• Group Dental, Vision, Life, AD&D and Disability coverage

• Paid Education Vacation and Sick Leave

• Paid institutional holidays, wellness leave, childcare leave and other paid leave programs

• Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans

• Employer paid life, AD&D and an illness-related reduced salary pay program

• Health Savings Account and Dependent Care Reimbursement flexible spending accounts

• Fertility benefits

• State of Texas longevity pay

• Extensive wellness, fitness, employee health programs and employee resource groups

FACULTY MENTOR

John V. Heymach, MD, PhD