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About Tonix*Tonix is a biopharmaceutical company, publicly traded on NASDAQ (ticker: TNXP). The Company is focused on commercializing, developing, discovering and licensing therapeutics to treat and prevent human disease. Tonix markets Zembrace® SymTouch® (sumatriptan injection) 3 mg and Tosymra® (sumatriptan nasal spray) 10 mg. Zembrace SymTouch and Tosymra are each indicated for the treatment of acute migraine with or without aura in adults. Tonix’s development portfolio is composed of central nervous system (CNS), rare disease, immunology and infectious disease product candidates. Tonix’s CNS development portfolio includes both small molecules and biologics to treat pain, neurologic, psychiatric and addiction conditions. The Company’s immunology portfolio includes biologics to address organ transplant rejection, autoimmunity, and cancer. Tonix’s infectious disease pipeline consists of a vaccine in development to prevent smallpox and monkeypox, which also serves as the live virus vaccine platform or recombinant pox vaccine platform for other infectious diseases.  Position OverviewTonix is looking for a Director, Protein Sciences and Computational Biology with extensive experience in computational biology, biophysical chemistry, macromolecular structure function relationship and AI/ML platforms. The candidate will be responsible for developing therapeutics in oncology, infectious diseases, and other indications. The positions are at Tonix’s Research and Development Center (RDC) which is the innovation and development arm of Tonix Pharmaceuticals. The individual in this position will work as part of the research team to deliver and optimize biological pipelines for clinical investigation. The individual in this position will participate in many aspects of therapeutic development, discovery, production, characterization, optimization, and program design. We are searching for self-motivated, resourceful, and adaptive scientists with an industry mindset and wide spectrum of expertise to join the RDC discovery and development team. This is a fast-paced challenging position offering a competitive compensation and benefits package. This position will report to the EVP, Infectious Diseases and will be based at the Tonix Research and Development Center in Frederick, Maryland.Essential DutiesCoordinate activities with other directors and run an independent research program Manage and drive Protein Sciences projects to support the development of next-generation protein therapiesManage and participate in hypothesis generation, production, and identifying of unique protein constructs with therapeutic applications to allow Tonix Pharmaceuticals competitively advance biologics’ pipeline in immunology, oncology, infectious diseases, and related fieldsEstablish criteria and workflows to enable efficient evaluation and selection of effective, and developable therapeutic candidatesLead computer-aided drug discovery within the Company’s pipelineShape and drive AI/ML innovation strategies applicable at various stages of R&D within Tonix pipelinePerform research and present reports on the status of current projects and potential benefits of future research developmentsAssess the latest technological advancements that are beneficial to protein engineering, structural biology, computational biology, and bioinformatics programs in the company pipelineLead specific project teams or participate in related project teams, propose new discovery and optimization path with industry mindsetElicit, synthesize, and manage the cross-functional inputs required for a robust development planEstablish and manage partnerships with CROs and consultantsUphold company mission and values through accountability, innovation, integrity, quality, and teamworkPerform ad-hoc work/special projects as necessary to support Tonix on various business initiativesSupervisory ResponsibilitiesRecruits, interviews, hires, and trains new staffProvides constructive and timely performance evaluationsIf necessary, handles discipline and termination of employees in accordance with company policyContributes to performance and compensation decisions such as: merit raises, bonuses, and promotions Supervise and mentor members of the team and be able to communicate well with peers Minimum QualificationsPh.D., or equivalent doctoral degree required plus 20 years of experienceEquipped with deep knowledge in protein engineering, protein expression and purification, protein characterization and analysis, including membrane proteins and large macromolecular complexesDemonstrated experience in macromolecule structure determination and analysis using X-ray crystallography, cryo-EM, and computational methodsAbility to apply cutting-edge ML/AI and data analytics, computational biology, virtual screening, and molecular dynamics for biologics and lead discovery (Python/C++ and Linux OS experience is preferred) Extensive experience in molecular cloning and vector design, RNA/DNA expression and purificationExperience with various expression systems and in protein characterization techniques including DLS, SPR, BLI, analytical centrifugation, thermophoresis, isothermal titration calorimetryExperience in expression and purification of viral glycoproteins in the correct biological context Knowledge of virus attenuation and engineering, VLP design, expression, and purification Ability to generate hypothesis to test ideas, use the data set to evaluate hypothesis and design new studiesStrong accomplishment record demonstrating the ability to perform independent, high-quality, creative, and impactful research in the field of Protein SciencesAbility for minimal travelDedicated team player who is able to withstand the high demands of a fast-paced environmentExcellent written and verbal communication skills are essentialStrong planning and organizational skillsComfortable working independently with minimal supervisionHighly organized, results driven, problem solver, and collaboratorDemonstrated ability to perform the essential duties of the position with or without accommodationRecruitment & Staffing AgenciesTonix does not accept agency resumes unless contacted directly by internal Tonix Talent Acquisition. Please do not forward resumes to Tonix employees or any other company location; Tonix is not responsible for any fees related to unsolicited resumes.Compensation & BenefitsAnnualized base salary ranges from $120,000 to $240,000 plus target incentive; actual salaries will vary and may be above or below this range commensurate with several factors including experience, education, training, location, and merit.Tonix provides a comprehensive compensation and benefits package which includes:Medical, Dental & Vision Insurance, Basic and Voluntary Life and AD&D Insurance, Short- and Long-Term Disability Insurance, Flexible Spending Accounts, Health Savings Account, and Employee Assistance ProgramsPet InsuranceRetirement Savings 401k with company match and annual discretionary stock optionsGenerous Paid Time Off, Sick Time, & Paid HolidaysCareer Development and Training Tonix provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, genetics, or any other characteristic protected by law. In addition to federal law requirements, Tonix complies with applicable state and local laws governing nondiscrimination in employment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfers, leaves of absence, compensation, and training. Tonix expressly prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic, information, disability, veteran status, or any other characteristic protected by law.