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Medical University of South Carolina UNIV - Post Doctoral Scholar - Surgery: GI & Laparoscopic Surgery in Charleston, South Carolina

FLSA: Salaried

Job Summary: A postdoctoral research fellow position is available in the Wang lab at the Department of Surgery, Medical University of South Carolina (MUSC). This position will involve in studying cellular therapy and its mechanistic insights in the treatment of type 1 diabetes or chronic pancreatitis with or without islet transplantation using state-of-the art technologies. Ongoing projects in the Wang lab are focused on translational research studying autoimmune response and islet death using iPSC, mesenchymal stem cells and other approaches. Other areas that can be pursed include studying the protective effects of engineered mesenchymal stem cells (MSCs), MSC-secreted exosomes, pancreatic beta cell development, induced pluripotent stem cells (iPSCs)-derived islet cells, in animal models and in clinical trials.

Candidates will receive advanced training from the investigational team to enhance their professional skills. Duties include, but are not limited to, assisting in design and conducting research within the research fields, developing new ideas that promote current research, and to prepare and publish scientific manuscripts. Fellows will be heavily involved in the ongoing clinical trials using AAT or MSC therapy in patients with type 1 diabetes or chronic pancreatitis.

Payscale Salary Range: UNIV-Band 0: Commensurate with experience.

Job Duties:

  • 30% - Performs cell culture experiments using various immunological techniques including ELISA, Flow cytometry, immunohistochemistry, confocal microscopy, and other technology. - (Essential)

  • 25% - Works with animal disease models (will establish mouse diabetic models, perform MSC infusion or other treatments, measure mouse glucose levels and other indicators, and perform tissue collection and analysis). - (Essential)

  • 20% - Primarily responsible for experimental design, data collection, and data analysis regarding cellular therapy and diabetes research. - (Essential)

  • 10% - Analyze patient samples for various clinical trials using ELISA, DNA extraction, and other methods. - (Essential)

  • 10% - Present research findings at internal meetings and conferences; assist in the organization of data for publication in peer-reviewed journals. Contribute to scientific literature search, research proposals, and grant applications. - (Essential)

  • 5% - Retains accurate records of research findings, along with analysis of results, in a detailed up-to-date laboratory notebook. - (Essential)

Minimum Experience and Training Requirements: A doctoral degree or equivalent (Ph.D. or M.D.) in appropriate fields. Strong passion for research, able to work as a team player but also can work independently. Ability to work with mice is a must. Experiences with basic molecular biology techniques (i.e., cell culture, protein and RNA analysis, animal handling/surgical techniques, etc), immunology, and neuroscience are preferred but are not required. Good scientific writing ability, strong oral communication skills are preferred. Please email CV to wangho@musc.edu .

Physical Requirements: Ability to perform job functions in an upright position. (Frequent) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb, using step stool. (Infrequent) Ability to work in temperature extremes (32? F to 100? F) when required due to assignments in cold rooms and/or foreign countries. (Infrequent) Ability to work in confined/cramped spaces. (Continuous) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Frequent) Ability to fully use both legs. (Frequent) Ability to reach in all directions, stretch, bend, while moving items/materials from both sitting and standing positions. (Frequent) Ability to maintain good olfactory sensory function/distinction. (Continuous) Ability to lift materials up to 20 lbs., unassisted. (Infrequent) Ability to lift and carry 4 liter waste material bottles a distance of 30 feet, unassisted. (Frequent) Ability to lift and carry 25-30 lbs. jugs of liquid a distance of 100 feet, unassisted. (Infrequent) Ability to lift file boxes, from floor level to counter tops, unassisted. (Frequent) Ability to push/ Ability to lift 40 lbs. centrifuge rotors from floor level to height of 40 inches, then down 20 inches into centrifuge drum, unassisted. (Infrequent) Ability to lift 25 lbs. boxes, from floor level to maximum height of 72 inches, unassisted. (Infrequent) Ability to push/pull file boxes from one location to another at floor level. (Frequent) Ability to maneuver heavy equipment on bench tops, 50 lbs. or greater, unassisted. (Frequent) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to maintain 20/20 vision, corrected. (Continuous) Ability to match or discriminate between colors, normally. (Continuous) Ability to hear and recognize various alarms emitting from work area systems. (Continuous) Ability to hear and/or understand conversations. (Continuous) Ability to work in a darkroom for processing film, etc. (Continuous) Ability to be qualified physically for respirator use, initially and annually. (Continuous)