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The Pre-Clinical Imaging Technologist will work closely with the preclinical and clinical imaging scientists to design and execute mouse studies using innovative PET/SPECT/CT, MRI, ultrasound and bioluminescence (BLI) imaging as well as the entire spectrum of conventional (e.g., caliper measurements, clinical scoring) endpoints to evaluate pre-clinical novel cancer therapies. The Technologist will take primary responsibility for one of the imaging modalities listed above but will also learn the other imaging modalities and participate in multimodality imaging research. They will serve as a back-up for other imaging modalities at the Lurie Family Imaging Center (LFIC), the pre-clinical arm of the Center for Biomedical Imaging in Oncology (CBIO), as appropriate and required. Must be able to understand and follow standard operating procedures and DFCI institutional guidelines and policies. Individual must understand and follow the local, state, federal regulations and guidelines pertaining to the safe handling of radioactive materials, MRI magnetic fields and the use of laboratory animals.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

• Coordinate and perform mouse imaging studies for cancer research and drug discovery using preclinical Siemens Inveon PET/SPECT/CT, Bruker MRI, BLI and ultrasound scanners.

• Will work in collaboration with Cyclotron physicist staff.

• Analyze and prepare imaging data for presentation and discussion with investigators.

• Participate in collaborative projects with CBIO/LFIC imaging technologists, scientists, clinicians and staff as well as counterparts in DFCI clinical environments to design and perform studies with a translational emphasis.

• Collaborate with and participate in the execution of other imaging modalities as appropriate and necessary.

• Ensure compliance local, state, and federal regulations and guidelines pertaining to the safe handling of radioactive materials and radiation equipment, MRI safety and the use of laboratory animals in addition to DFCI institutional guidelines and policies.

• Operate and maintain scanners and other equipment with support and guidance of the CBIO Pre-clinical and clinical Imaging Physicists and the DFCI Radiation Safety Officer.

• Participate actively in relevant professional organizations in nuclear medicine, MRI, ultrasound, pre-clinical research, and laboratory animal science.

• Perform in vivo and in vitro irradiation studies using Precision X-Rad 225Cx.

• Induce and maintain anesthesia and administer medications, fluids and blood products as prescribed by the scientist (IV, IP, SQ, PO administration).

• Will assist with the establishment and maintenance of mouse cancer models (e.g. by injection or minor surgery).

• Maintain treatment records and inventory of all pharmaceuticals, equipment and supplies, and help with other administrative tasks.

SUPERVISORY RESPONSIBILITIES:

No direct reports.

MINIMUM JOB QUALIFICATIONS: ( Education, certifications, years of experience )

1. High school diploma required. A BA/BS in Animal Science or related life science preferred.

2. LAT preferred.

KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:

• 1-2 years of work experience in small animal studies in academia or industry preferred.

• Knowledge in animal studies including IP, IV, SQ injections, oral gavage, blood collection, and minor surgical procedures preferred (e.g., renal capsule implants, mammary fat pad implants, prostate implants).

• Prior preclinical PET/SPECT/CT, MRI, BLI and ultrasound experience preferred.

• Must be organized and meticulous in record keeping.

• Ability to communicate and collaborate with members of a multidisciplinary team.

• Excellent interpersonal skills are required.

• Individual must be able to safely handle, restrain, perform treatments and euthanize laboratory mice as directed. An understanding of mouse breeding colony maintenance required for establishing breeding colony pairs, sexing animals, weaning pups and entering colony data on cage cards and in computer database.

• Previous experience working with infectious agents (ABSL-2/3 level) would be helpful but not required. In-house training will be provided prior to working in ABSL-2/3 areas.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

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